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Vetmedin is used to manage mild, moderate, or severe congestive heart failure in dogs caused by atrioventricular valvular insufficiency or dilated cardiomyopathy. It differs from other commonly used heart drugs because it helps the heart pump more efficiently. Vetmedin requires a prescription from your veterinarian.
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Vetmedin is used in dogs 6 months of age or older for the management of mild, moderate, or severe congestive heart failure due to atrioventricular valvular insufficiency or dilated cardiomyopathy. Vetmedin is available by prescription as 1.25mg, 2.5mg, 5mg and 10mg scored, porcine derived beef flavored, chewable tablets. The usual dose for dogs is 0.23mg per pound divided into 2 portions to be given 12 hours apart. The portion to be given should be to the nearest 1/2 tablet increment.
Vetmedin is not for use in humans. Do not give this medication to animals allergic to it. Do not give to animals with hypertrophic cardiomyopathy, aortic stenosis, or any other condition where an increase in cardiac output is not recommended. Do not give this medication to dogs less than 6 months of age. Do not give this medication to pregnant or lactating animals.
Breeds at risk for AVVI are small to medium-sized dogs such as Chihuahuas, toy poodles, Boston terrier, and Pomeranians. The middle-aged large and giant breeds are more prone to DCM, like the Newfoundland, St. Bernard, Boxer, Great Dane, and Doberman pinscher.
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In response to a shortage of Vetmedin (pimobendan), the U.S. Food and Drug Administration does not intend to object to the temporary importation of Vetmedin capsules and Vetmedin chews by Boehringer Ingelheim Animal Health USA, Inc., from Canada, the United Kingdom and Ireland to immediately increase the availability of Vetmedin in the United States. Vetmedin is a critical medication used to treat dogs with congestive heart failure due to valvular insufficiency or dilated cardiomyopathy. There is no FDA-approved alternative to Vetmedin. This measure should help fill recent gaps in the supply of Vetmedin in the U.S.
Vetmedin is used mostly in dogs with defective heart valves (valvular insufficiency or regurgitation, often as a result of nodular endocardiosis). If the valves in the heart fail to operate properly, blood flows back when the valves are supposed to be closed, making the heart less efficient as a pump. This also makes a whooshing sound in the heart, called a heart murmur, which vets can hear using a stethoscope. Vetmedin acts on the muscle of the heart and of blood vessel walls, helping the heart to beat more efficiently.
Vetmedin is not suitable for dogs under the age of six months and should not be given to pregnant or nursing dogs. Care should also be taken with animals suffering from conditions such as diabetes and who are already taking other medications. Your vet will be able to determine if there is a risk of interactions with any other pet medication.
Vetmedin can only be obtained with a prescription from the vet. Buying prescription pet meds online still requires a written prescription, which must be sent with the order before the drugs can be supplied.
hi just wondering if we can break the capsule and place the ingredients inside into some water and syringe to insert into our dogs mouth as she finds it hard to swallow it and we have a hard time getting it down her throat. which actually causes more stress to our dog.
Vetmedin (pimobendan) is indicated for the management of the signs of mild, moderate, or severe (modified NYHA Class II, III, or IV) congestive heart failure in dogs due to atrioventricular valvular insufficiency (AVVI) or dilated cardiomyopathy (DCM). Vetmedin is indicated for use with concurrent therapy for congestive heart failure (e.g., furosemide, etc.) as appropriate on a case-by-case basis.
The safety of Vetmedin has not been established in dogs with asymptomatic heart disease or in heart failure caused by etiologies other than AVVI or DCM. The safe use of Vetmedin has not been evaluated in dogs younger than 6 months of age, dogs with congenital heart defects, dogs with diabetes mellitus or other serious metabolic diseases, dogs used for breeding, or pregnant or lactating bitches.
Vetmedin for dogs contains the active ingredient Pimobendan. It is used for the pre-clinical treatment of dilated cardiomyopathy and preclinical mitral valve disease. Vetmedin chewable tablets for dogs are also used for the treatment of congestive heart failure caused by dilated cardiomyopathy and valvular insufficiency. It is an oral tablet and should be administered to a dog twice a day, half an hour before food is given.
Vetmedin is a medicine for dogs with pre-clinical treatment of dilated cardiomyopathy and preclinical mitral valve disease. It can also be used in dogs that have congestive heart failure caused by valvular insufficiency (mitral and/or tricuspid regurgitation) or dilated cardiomyopathy. It is designed to ease blood flow to the heart and increases its efficiency as a pump. It comes in the form of chewable tablets and is available in a variety of doses. Vetmedin should be taken as directed by your vet at an appropriate dosage level.
Vetmedin should be used only on the recommendation of a veterinarian and under their direct supervision. In addition, pimobendan, the active ingredient in Vetmedin, has not been researched at length in dogs with conditions such as heart defects, diabetes, or puppies less than 6 months of age.
A consequence of the use of triple therapy is the need to administer at least three medicines orally to dogs with CHF. In human medicine, compliance in patients taking their medicines as directed is inversely related to the complexity of the regimen and the number of doses prescribed per day . Fixed-dose combination products have been shown to reduce the risk of non-compliance in humans, including those with cardiovascular disease, and a number of such products are available .
The only AE with a significant difference between groups was emesis, which was significantly less frequent in the IVP group than in the Control I (p = 0.0034) and Control I + II (p = 0.0042) groups; significance was approached (p = 0.056) for the difference in emesis between the IVP and Control II groups. The number (%) of dogs with emesis was 3 (8.8%) in the IVP group, 7 (50.0%) in Control I, 6 (31.6%) in Control II, and 13 (39.4%) in Control I + II.
Dogs in the IVP and both control groups showed significant improvement from baseline for the GCS and some secondary endpoints including NYHA class, and FETCH and pulmonary edema scores. This can be explained by the fact that all dogs were treated with an ACEI (benazepril) and pimobendan after D0, whereas prior to D0 only 79.1% of dogs received an ACEI and 49.3% received pimobendan, reflective of first opinion practice in Japan. Frequency of use and dosages of amlodipine, furosemide, spironolactone, and torasemide were similar prior to and after D0. The improvement vs. baseline in all groups provides some evidence that benazepril and pimobendan in combination are effective in improving clinical signs in dogs with CHF caused by MMVD. To our knowledge, the combination of benazepril and pimobendan in dogs with CHF has not been tested previously in controlled prospective studies, although their combined use in a retrospective study has been reported .
First, a study population size of 67 dogs is relatively low for a field study. The sample size was determined by the regulatory requirement for a minimum of 60 cases, and proved to be sufficient to test the primary objective of the study, i.e., demonstration of non-inferior efficacy for the primary endpoint with the defined δ of 20%. The limited number of dogs means that the study had low power to detect subtle differences in efficacy between the groups or to detect uncommon AEs; for example, the study had only 49% power to detect AEs with a true incidence of 1%.
Third, we studied dogs at Japanese clinics with CHF in NYHA classes III and IV caused by MMVD. Diuretics were used in fewer cases (30%) than is standard in many other countries, even though all dogs had evidence of pulmonary edema at baseline. The results, therefore, cannot be simply generalized to other settings. 041b061a72